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POE Immunoassay: Plate-based oligonucleotide electro-chemiluminescent immunoassay for the quantification of nucleic acids in biological matrices

Oligonucleotide therapeutics use short interfering RNA (siRNA) or antisense oligonucleotide (ASO) molecules to exploit endogenous systems—neutralizing target RNA to prevent subsequent protein translation. While the potential clinical application is vast, delivery efficiency and extrahepatic targetin...

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Detalles Bibliográficos
Autores principales: Thayer, Mai B., Humphreys, Sara C., Chung, Kyu S., Lade, Julie M., Cook, Kevin D., Rock, Brooke M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319975/
https://www.ncbi.nlm.nih.gov/pubmed/32591626
http://dx.doi.org/10.1038/s41598-020-66829-6