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Overexpression of PGC-1α influences the mitochondrial unfolded protein response (mtUPR) induced by MPP(+) in human SH-SY5Y neuroblastoma cells

Parkinson’s disease (PD) is a common dyskinesia disease, the mitochondrial unfolded protein response (mtUPR) may be directly or indirectly involved in the occurrence and development of PD, although the exact mechanism is unclear. We established a dopaminergic neuronal-like cell model of PD, by overe...

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Detalles Bibliográficos
Autores principales: Cai, Yousheng, Shen, Hui, Weng, Huidan, Wang, Yingqing, Cai, Guoen, Chen, Xiaochun, Ye, Qinyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320005/
https://www.ncbi.nlm.nih.gov/pubmed/32591623
http://dx.doi.org/10.1038/s41598-020-67229-6