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The importance of the AMPK gamma 1 subunit in metformin suppression of liver glucose production

Metformin has been used to treat patients with type 2 diabetes for over 60 years, however, its mechanism of action is still not completely understood. Our previous reports showed that high-fat-diet (HFD)-fed mice with liver-specific knockout of both AMPK catalytic α1 and α2 subunits exhibited signif...

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Detalles Bibliográficos
Autores principales: An, Hongying, Wang, Yu, Qin, Caolitao, Li, Mingsong, Maheshwari, Akhil, He, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320014/
https://www.ncbi.nlm.nih.gov/pubmed/32591547
http://dx.doi.org/10.1038/s41598-020-67030-5