Imaging mass spectrometry to visualise increased acetylcholine in lungs of asthma model mice

Acetylcholine (ACh) is a crucial neurotransmitter that is involved in airway constriction. In fact, excessive ACh binding to M3 muscarinic receptor leads to airflow obstruction via smooth muscle contraction. Previous studies have suggested cholinergic malfunction in the pathogenesis of asthma; howev...

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Detalles Bibliográficos
Autores principales: Matsuda, Takeshi, Suzuki, Yuzo, Fujisawa, Tomoyuki, Suga, Yasunori, Saito, Nobuyuki, Suda, Takafumi, Yao, Ikuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320054/
https://www.ncbi.nlm.nih.gov/pubmed/32367293
http://dx.doi.org/10.1007/s00216-020-02670-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320054/
https://www.ncbi.nlm.nih.gov/pubmed/32367293
http://dx.doi.org/10.1007/s00216-020-02670-0

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