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Breast cancer colonization by Fusobacterium nucleatum accelerates tumor growth and metastatic progression

Fusobacterium nucleatum is an oral anaerobe recently found to be prevalent in human colorectal cancer (CRC) where it is associated with poor treatment outcome. In mice, hematogenous F. nucleatum can colonize CRC tissue using its lectin Fap2, which attaches to tumor-displayed Gal-GalNAc. Here, we sho...

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Detalles Bibliográficos
Autores principales: Parhi, Lishay, Alon-Maimon, Tamar, Sol, Asaf, Nejman, Deborah, Shhadeh, Amjad, Fainsod-Levi, Tanya, Yajuk, Olga, Isaacson, Batya, Abed, Jawad, Maalouf, Naseem, Nissan, Aviram, Sandbank, Judith, Yehuda-Shnaidman, Einav, Ponath, Falk, Vogel, Jörg, Mandelboim, Ofer, Granot, Zvi, Straussman, Ravid, Bachrach, Gilad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320135/
https://www.ncbi.nlm.nih.gov/pubmed/32591509
http://dx.doi.org/10.1038/s41467-020-16967-2