Development of Label-Free Impedimetric Immunosensors for IKZF1 and IKZF3 Femtomolar Detection for Monitoring Multiple Myeloma Patients Treated with Lenalidomide

Lenalidomide is an immunomodulatory drug (IMiD) used to treat multiple myeloma (MM) patients. Lenalidomide destroys MM cells by inducing ubiquitination and the consequent degradation of Ikaros family zinc finger proteins 1 and 3 (IKZF1 and IKZF3). High expression of IKZF1 and IKZF3 in MM results in...

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Detalles Bibliográficos
Autores principales: Abdulkarim, Haya, Zourob, Mohammed, Siaj, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320141/
https://www.ncbi.nlm.nih.gov/pubmed/32591583
http://dx.doi.org/10.1038/s41598-020-67241-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320141/
https://www.ncbi.nlm.nih.gov/pubmed/32591583
http://dx.doi.org/10.1038/s41598-020-67241-w

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