Hydroxamic acid derivatives as HDAC1, HDAC6 and HDAC8 inhibitors with antiproliferative activity in cancer cell lines

Histone deacetylases (HDACs) belong to a family of enzymes that remove acetyl groups from the ɛ-amino of histone and nonhistone proteins. Additionally, HDACs participate in the genesis and development of cancer diseases as promising therapeutic targets to treat cancer. Therefore, in this work, we de...

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Detalles Bibliográficos
Autores principales: Sixto-López, Yudibeth, Gómez-Vidal, José Antonio, de Pedro, Nuria, Bello, Martiniano, Rosales-Hernández, Martha Cecilia, Correa-Basurto, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320180/
https://www.ncbi.nlm.nih.gov/pubmed/32591593
http://dx.doi.org/10.1038/s41598-020-67112-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320180/
https://www.ncbi.nlm.nih.gov/pubmed/32591593
http://dx.doi.org/10.1038/s41598-020-67112-4

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