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Identifying novel genetic alterations in pediatric acute lymphoblastic leukemia based on copy number analysis

Copy number variations (CNVs) analysis may reveal molecular biomarkers and provide information on the pathogenesis of acute lymphoblastic leukemia (ALL). We investigated the gene copy number in childhood ALL by microarray and select three new recurrent CNVs to evaluate by real-time PCR assay: DMBT1,...

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Detalles Bibliográficos
Autores principales: Batista-Gomes, Jéssica Almeida, Mello, Fernando Augusto Rodrigues, de Oliveira, Edivaldo Herculano Corrêa, de Souza, Michel Platini Caldas, Wanderley, Alayde Vieira, da Costa Pantoja, Laudreisa, dos Santos, Ney Pereira Carneiro, Khayat, Bruna Cláudia Meireles, Khayat, André Salim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320540/
https://www.ncbi.nlm.nih.gov/pubmed/32607130
http://dx.doi.org/10.1186/s13039-020-00491-5