Vargas: heuristic-free alignment for assessing linear and graph read aligners

MOTIVATION: Read alignment is central to many aspects of modern genomics. Most aligners use heuristics to accelerate processing, but these heuristics can fail to find the optimal alignments of reads. Alignment accuracy is typically measured through simulated reads; however, the simulated location ma...

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Detalles Bibliográficos
Autores principales: Darby, Charlotte A, Gaddipati, Ravi, Schatz, Michael C, Langmead, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320598/
https://www.ncbi.nlm.nih.gov/pubmed/32321164
http://dx.doi.org/10.1093/bioinformatics/btaa265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320598/
https://www.ncbi.nlm.nih.gov/pubmed/32321164
http://dx.doi.org/10.1093/bioinformatics/btaa265

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