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Vargas: heuristic-free alignment for assessing linear and graph read aligners
MOTIVATION: Read alignment is central to many aspects of modern genomics. Most aligners use heuristics to accelerate processing, but these heuristics can fail to find the optimal alignments of reads. Alignment accuracy is typically measured through simulated reads; however, the simulated location ma...
Autores principales: | Darby, Charlotte A, Gaddipati, Ravi, Schatz, Michael C, Langmead, Ben |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320598/ https://www.ncbi.nlm.nih.gov/pubmed/32321164 http://dx.doi.org/10.1093/bioinformatics/btaa265 |
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