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MIAMI––a tool for non-targeted detection of metabolic flux changes for mode of action identification

SUMMARY: Mass isotopolome analysis for mode of action identification (MIAMI) combines the strengths of targeted and non-targeted approaches to detect metabolic flux changes in gas chromatography/mass spectrometry datasets. Based on stable isotope labeling experiments, MIAMI determines a mass isotopo...

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Detalles Bibliográficos
Autores principales: Dudek, Christian-Alexander, Reuse, Carsten, Fuchs, Regine, Hendriks, Janneke, Starck, Veronique, Hiller, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320603/
https://www.ncbi.nlm.nih.gov/pubmed/32324861
http://dx.doi.org/10.1093/bioinformatics/btaa251