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Inhibited Metastasis and Amplified Chemotherapeutic Effects by Epigene-Transfection Based on a Tumor-Targeting Nanoparticle

PURPOSE: Tumor metastasis and drug resistance have always been vital aspects to cancer mortality and prognosis. To compromise metastasis and drug resistance, a nanoparticle IPPD-PHF2 (IR780/PLGA-PEI(Dox)-PHF2) has been engineered to accomplish efficient targeted epigenotherapy forced by PHF2-induced...

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Detalles Bibliográficos
Autores principales: Wang, Mengzhu, Wang, Zhigang, Qiao, Bin, Cao, Jin, Quan, Luya, Luo, Yuanli, Qi, Hanwen, Zhong, Xiaowen, He, Yubei, Zhang, Xianquan, Hao, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320902/
https://www.ncbi.nlm.nih.gov/pubmed/32606690
http://dx.doi.org/10.2147/IJN.S247567