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AMPK α1 Downregulates ROS Levels Through Regulating Trx Leading to Dysfunction of Apoptosis in Non-Small Cell Lung Cancer

PURPOSE: AMP-activated protein kinase α1 (AMPK α1) associates closely with cancers. However, the relationship between AMPK α1 and non-small cell lung cancer (NSCLC) is not fully understood. In this study, we aim to explore the role and mechanism of AMPK α1 in NSCLC initiation and progression. MATERI...

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Detalles Bibliográficos
Autores principales: Gong, Daohui, Li, Ying, Wang, Yuxiu, Chi, Beiyuan, Zhang, Jun, Gu, Jianjun, Yang, JunJun, Xu, Xingxiang, Hu, Suwei, Min, Lingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320905/
https://www.ncbi.nlm.nih.gov/pubmed/32606805
http://dx.doi.org/10.2147/OTT.S236235