Cargando…
AMPK α1 Downregulates ROS Levels Through Regulating Trx Leading to Dysfunction of Apoptosis in Non-Small Cell Lung Cancer
PURPOSE: AMP-activated protein kinase α1 (AMPK α1) associates closely with cancers. However, the relationship between AMPK α1 and non-small cell lung cancer (NSCLC) is not fully understood. In this study, we aim to explore the role and mechanism of AMPK α1 in NSCLC initiation and progression. MATERI...
Autores principales: | Gong, Daohui, Li, Ying, Wang, Yuxiu, Chi, Beiyuan, Zhang, Jun, Gu, Jianjun, Yang, JunJun, Xu, Xingxiang, Hu, Suwei, Min, Lingfeng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320905/ https://www.ncbi.nlm.nih.gov/pubmed/32606805 http://dx.doi.org/10.2147/OTT.S236235 |
Ejemplares similares
-
The demographic and treatment options for patients with large cell neuroendocrine carcinoma of the lung
por: Gu, Jianjun, et al.
Publicado: (2019) -
miR-137 represses migration and cell motility by targeting COX-2 in non-small cell lung cancer
por: Luo, Yutu, et al.
Publicado: (2022) -
Licochalcone a Induces ROS-Mediated Apoptosis through TrxR1 Inactivation in Colorectal Cancer Cells
por: Wu, Peng, et al.
Publicado: (2020) -
β-Sitosterol targets Trx/Trx1 reductase to induce apoptosis in A549 cells via ROS mediated mitochondrial dysregulation and p53 activation
por: Rajavel, Tamilselvam, et al.
Publicado: (2018) -
Aberrant microRNA-137 promoter methylation is associated with lymph node metastasis and poor clinical outcomes in non-small cell lung cancer
por: Min, Lingfeng, et al.
Publicado: (2018)