Cargando…

Aurora-B Promotes Osteosarcoma Cell Growth and Metastasis Through Activation of the NPM1/ERK/NF-κβ/MMPs Axis

PURPOSE: Osteosarcoma (OS) is the most common primary malignant tumor of the bone in young adolescents and children. We explored the underlying mechanism of Aurora-B in promoting OS cell proliferation and metastasis. PATIENT AND METHODS: Bioinformatics was employed to predict the substrate of Aurora...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Honghai, Zhou, Yang, Peng, Aifen, Liu, Jiaming, Wu, Xin, Chen, Wenzhao, Liu, Zhili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320907/
https://www.ncbi.nlm.nih.gov/pubmed/32606971
http://dx.doi.org/10.2147/CMAR.S252847