A Multi-Species Phenotypic Screening Assay for Leishmaniasis Drug Discovery Shows That Active Compounds Display a High Degree of Species-Specificity

High genetic and phenotypic variability between Leishmania species and strains within species make the development of broad-spectrum antileishmanial drugs challenging. Thus, screening panels consisting of several diverse Leishmania species can be useful in enabling compound prioritization based on t...

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Detalles Bibliográficos
Autores principales: Alcântara, Laura M., Ferreira, Thalita C. S., Fontana, Vanessa, Chatelain, Eric, Moraes, Carolina B., Freitas-Junior, Lucio H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321149/
https://www.ncbi.nlm.nih.gov/pubmed/32486239
http://dx.doi.org/10.3390/molecules25112551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321149/
https://www.ncbi.nlm.nih.gov/pubmed/32486239
http://dx.doi.org/10.3390/molecules25112551

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