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Inhibitory Effects of Tangeretin, a Citrus Peel-Derived Flavonoid, on Breast Cancer Stem Cell Formation through Suppression of Stat3 Signaling

Breast cancer stem cells (BCSCs) are responsible for tumor chemoresistance and recurrence. Targeting CSCs using natural compounds is a novel approach for cancer therapy. A CSC-inhibiting compound was purified from citrus extracts using silica gel, gel filtration and high-pressure liquid chromatograp...

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Detalles Bibliográficos
Autores principales: Ko, Yu-Chan, Choi, Hack Sun, Liu, Ren, Kim, Ji-Hyang, Kim, Su-Lim, Yun, Bong-Sik, Lee, Dong-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321155/
https://www.ncbi.nlm.nih.gov/pubmed/32503228
http://dx.doi.org/10.3390/molecules25112599