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A Co-Delivery System of Curcumin and p53 for Enhancing the Sensitivity of Drug-Resistant Ovarian Cancer Cells to Cisplatin

In order to enhance the sensitivity of drug-resistant ovarian cancer cells to cisplatin (DDP), a co-delivery system was designed for simultaneous delivery of curcumin (CUR) and p53 DNA. Firstly, the bifunctional peptide K14 composed of tumor targeting peptide (tLyP-1) and nuclear localization signal...

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Detalles Bibliográficos
Autores principales: Guo, Xinli, Fang, Zhou, Zhang, Min, Yang, Deyu, Wang, Shuyue, Liu, Kehai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321199/
https://www.ncbi.nlm.nih.gov/pubmed/32512936
http://dx.doi.org/10.3390/molecules25112621