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Development of Resistance to Endoplasmic Reticulum Stress-Inducing Agents in Mouse Leukemic L1210 Cells

Four new variants of L1210 cells resistant to endoplasmic reticulum (ER) stressors, tunicamycin (S(Tun)), thapsigargin (S(Thap)), bortezomib (S(Bor)), and MG-132 (S(MG-132)), were developed via an 18-month periodic cultivation in culture medium with a gradual increase in substance concentration. Mul...

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Detalles Bibliográficos
Autores principales: Cagala, Martin, Pavlikova, Lucia, Seres, Mario, Kadlecikova, Karolina, Breier, Albert, Sulova, Zdena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321222/
https://www.ncbi.nlm.nih.gov/pubmed/32481618
http://dx.doi.org/10.3390/molecules25112517