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Cryptococcus neoformans Capsular GXM Conformation and Epitope Presentation: A Molecular Modelling Study

The pathogenic encapsulated Cryptococcus neoformans fungus causes serious disease in immunosuppressed hosts. The capsule, a key virulence factor, consists primarily of the glucuronoxylomannan polysaccharide (GXM) that varies in composition according to serotype. While GXM is a potential vaccine targ...

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Detalles Bibliográficos
Autores principales: Kuttel, Michelle M., Casadevall, Arturo, Oscarson, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321252/
https://www.ncbi.nlm.nih.gov/pubmed/32517333
http://dx.doi.org/10.3390/molecules25112651