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Cryptococcus neoformans Capsular GXM Conformation and Epitope Presentation: A Molecular Modelling Study
The pathogenic encapsulated Cryptococcus neoformans fungus causes serious disease in immunosuppressed hosts. The capsule, a key virulence factor, consists primarily of the glucuronoxylomannan polysaccharide (GXM) that varies in composition according to serotype. While GXM is a potential vaccine targ...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321252/ https://www.ncbi.nlm.nih.gov/pubmed/32517333 http://dx.doi.org/10.3390/molecules25112651 |