Conjugation of Doxorubicin to siRNA Through Disulfide-based Self-immolative Linkers

Co-delivery systems of siRNA and chemotherapeutic drugs have been developed as an attractive strategy to optimize the efficacy of chemotherapy towards cancer cells with multidrug resistance. In these typical systems, siRNAs are usually associated to drugs within a carrier but without covalent intera...

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Detalles Bibliográficos
Autores principales: Gauthier, Florian, Bertrand, Jean-Rémi, Vasseur, Jean-Jacques, Dupouy, Christelle, Debart, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321315/
https://www.ncbi.nlm.nih.gov/pubmed/32545345
http://dx.doi.org/10.3390/molecules25112714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321315/
https://www.ncbi.nlm.nih.gov/pubmed/32545345
http://dx.doi.org/10.3390/molecules25112714

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