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Conjugation of Doxorubicin to siRNA Through Disulfide-based Self-immolative Linkers
Co-delivery systems of siRNA and chemotherapeutic drugs have been developed as an attractive strategy to optimize the efficacy of chemotherapy towards cancer cells with multidrug resistance. In these typical systems, siRNAs are usually associated to drugs within a carrier but without covalent intera...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321315/ https://www.ncbi.nlm.nih.gov/pubmed/32545345 http://dx.doi.org/10.3390/molecules25112714 |