Design, Synthesis, Antitumor Activity and Molecular Docking Study of Novel 5-Deazaalloxazine Analogs

Protein tyrosine kinases (PTKs) are the most potential therapeutic targets for cancer. Herein, we present a sound rationale for synthesis of a series of novel 2-(methylthio), 2-(substituted alkylamino), 2-(heterocyclic substituted), 2-amino, 2,4-dioxo and 2-deoxo-5-deazaalloxazine derivatives by app...

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Detalles Bibliográficos
Autores principales: Mahmoud, Sawsan, Samaha, Doaa, Mohamed, Mosaad S., Abou Taleb, Nageh A., Elsawy, Mohamed A., Nagamatsu, Tomohisa, Ali, Hamed I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321323/
https://www.ncbi.nlm.nih.gov/pubmed/32481639
http://dx.doi.org/10.3390/molecules25112518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321323/
https://www.ncbi.nlm.nih.gov/pubmed/32481639
http://dx.doi.org/10.3390/molecules25112518

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