Albumin-Binding PSMA Radioligands: Impact of Minimal Structural Changes on the Tissue Distribution Profile

The concept of using ibuprofen as an albumin-binding entity was recently demonstrated by the development of [(177)Lu]Lu-Ibu-PSMA-01. In the present study, we designed a novel ibuprofen-containing radioligand (Ibu-PSMA-02) with subtle structural changes regarding the linker entity in order to investi...

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Detalles Bibliográficos
Autores principales: Deberle, Luisa M., Tschan, Viviane J., Borgna, Francesca, Sozzi-Guo, Fan, Bernhardt, Peter, Schibli, Roger, Müller, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321364/
https://www.ncbi.nlm.nih.gov/pubmed/32486054
http://dx.doi.org/10.3390/molecules25112542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321364/
https://www.ncbi.nlm.nih.gov/pubmed/32486054
http://dx.doi.org/10.3390/molecules25112542

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