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Synthesis and In Vitro Cytotoxicity and Antibacterial Activity of Novel 1,2,3-Triazol-5-yl-Phosphonates

Novel 1,2,3-triazol-5-yl-phosphonates were prepared by the copper(I)-catalyzed domino reaction of phenylacetylene, organic azides and dialkyl phosphites. The process was optimized on the synthesis of the dibutyl (1-benzyl-4-phenyl-1H-1,2,3-triazol-5-yl)phosphonate in respect of the catalyst, the bas...

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Detalles Bibliográficos
Autores principales: Tripolszky, Anna, Tóth, Emese, Szabó, Pál Tamás, Hackler, László, Kari, Beáta, Puskás, László G., Bálint, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321403/
https://www.ncbi.nlm.nih.gov/pubmed/32517229
http://dx.doi.org/10.3390/molecules25112643