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Overexpression of 14-3-3δ Predicts Poor Prognosis in Extrahepatic Cholangiocarcinoma Patients

The protein 14-3-3δ interacts with Trp53 to maintain G2 arrest and thus regulates the cell cycle. Though dysfunction of 14-3-3δ caused by hyper-methylation of CpG islands was reported in several carcinomas, the exact role of this protein in the development of extrahepatic cholangiocarcinoma has not...

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Detalles Bibliográficos
Autores principales: Wu, Qiao, Fan, Hua, Lang, Ren, Li, Xianliang, Zhang, Xingmao, Lv, Shaocheng, He, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321506/
https://www.ncbi.nlm.nih.gov/pubmed/32685532
http://dx.doi.org/10.1155/2020/8435420