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GLP-1/GLP-1R Signaling Regulates Ovarian PCOS-Associated Granulosa Cells Proliferation and Antiapoptosis by Modification of Forkhead Box Protein O1 Phosphorylation Sites

As the major cause of female anovulatory infertility, polycystic ovary syndrome (PCOS) affects a great proportion of women at childbearing age. Although glucagon-like peptide 1 receptor agonists (GLP-IRAs) show therapeutic effects for PCOS, its target and underlying mechanism remains elusive. In the...

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Detalles Bibliográficos
Autores principales: Sun, Zhihua, Li, Peiyi, Wang, Xiao, Lai, Shuchang, Qiu, Hong, Chen, Zhi, Hu, Shidi, Yao, Jie, Shen, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321515/
https://www.ncbi.nlm.nih.gov/pubmed/32655632
http://dx.doi.org/10.1155/2020/1484321