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An all-silk-derived functional nanosphere matrix for sequential biomolecule delivery and in situ osteochondral regeneration
Endogenous repair of osteochondral defect is usually limited by the insufficient number of cells in the early stage and incomplete cell differentiation in the later stage. The development of drug delivery systems for sequential release of pro-migratory and pro-chondrogenic molecules to induce endoge...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321772/ https://www.ncbi.nlm.nih.gov/pubmed/32637747 http://dx.doi.org/10.1016/j.bioactmat.2020.05.003 |