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Tumor-Secreted Exosomal lncRNA POU3F3 Promotes Cisplatin Resistance in ESCC by Inducing Fibroblast Differentiation into CAFs

Cancer-associated fibroblasts (CAFs), an activated subpopulation of fibroblasts, occupy a central position in the tumor microenvironment and have been shown to promote chemoresistance in multiple cancer types by secreting inflammatory cytokines. Herein, we report that tumor-secreted exosomal long no...

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Detalles Bibliográficos
Autores principales: Tong, Yusuo, Yang, Lili, Yu, Changhua, Zhu, Weiguo, Zhou, Xilei, Xiong, Yaozu, Wang, Wanwei, Ji, Fuzhi, He, Dongcheng, Cao, Xiufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321817/
https://www.ncbi.nlm.nih.gov/pubmed/32637576
http://dx.doi.org/10.1016/j.omto.2020.05.014