LEM2 phase separation governs ESCRT-mediated nuclear envelope reformation

During cell division, remodeling of the nuclear envelope (NE) enables chromosome segregation by the mitotic spindle(1). The reformation of sealed nuclei requires Endosomal Sorting Complexes Required for Transport (ESCRTs) and LEM2, a transmembrane ESCRT adapter(2–4). Here, we show how LEM2’s ability...

Descripción completa

Detalles Bibliográficos
Autores principales: von Appen, Alexander, LaJoie, Dollie, Johnson, Isabel E., Trnka, Michael J., Pick, Sarah M., Burlingame, Alma L., Ullman, Katharine S., Frost, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321842/
https://www.ncbi.nlm.nih.gov/pubmed/32494070
http://dx.doi.org/10.1038/s41586-020-2232-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321842/
https://www.ncbi.nlm.nih.gov/pubmed/32494070
http://dx.doi.org/10.1038/s41586-020-2232-x

Ejemplares similares