Hydrophobic interactions at subsite S1′ of human dipeptidyl peptidase IV contribute significantly to the inhibitory effect of tripeptides

Functional inhibitory peptides of human dipeptidyl peptidase 4 (hDPP4) have been highly anticipated as the active ingredient of functional food for type II diabetes; however, the molecular mechanism of hDPP4 inhibition remains unclear. In this study, we focused on dipeptides and tripeptides, which d...

Descripción completa

Detalles Bibliográficos
Autores principales: Araki, Mitsugu, Kanegawa, Norimasa, Iwata, Hiroaki, Sagae, Yukari, Ito, Keisuke, Masuda, Katsuyoshi, Okuno, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322046/
https://www.ncbi.nlm.nih.gov/pubmed/32613113
http://dx.doi.org/10.1016/j.heliyon.2020.e04227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322046/
https://www.ncbi.nlm.nih.gov/pubmed/32613113
http://dx.doi.org/10.1016/j.heliyon.2020.e04227

Ejemplares similares