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Chemical reactivity and bioactivity properties of pyrazinamide analogs of acetylsalicylic acid and salicylic acid using conceptual density functional theory

Conventional drugs used to treat Tuberculosis (TB) are becoming ineffective due to the occurrence of multiple drug resistant strains of tuberculosis (TB). This has made the TB disease a a serious global health dilemma. Hence, there is desperate necessity for the advancement of new drugs. In this wor...

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Detalles Bibliográficos
Autores principales: Villagracia, Al Rey, Ong, Hui Lin, Lagua, Faith Marie, Alea, Glenn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322055/
https://www.ncbi.nlm.nih.gov/pubmed/32613118
http://dx.doi.org/10.1016/j.heliyon.2020.e04239