Co-targeting Mitochondrial Ca(2+) Homeostasis and Autophagy Enhances Cancer Cells' Chemosensitivity

Mitochondria are important cell death checkpoints, and mitochondrial Ca(2+) overload is considered as a potent apoptotic intrinsic pathway inducer. Here, we report that this Ca(2+) apoptosis link is largely ineffective in inducing cell-death just by itself and required a concomitant inhibition of au...

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Detalles Bibliográficos
Autores principales: Dubois, Charlotte, Kondratskyi, Artem, Bidaux, Gabriel, Noyer, Lucile, Vancauwenberghe, Eric, Farfariello, Valério, Toillon, Robert-Allain, Roudbaraki, Morad, Tierny, Dominique, Bonnal, Jean-Louis, Prevarskaya, Natalia, Vanden Abeele, Fabien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322071/
https://www.ncbi.nlm.nih.gov/pubmed/32585596
http://dx.doi.org/10.1016/j.isci.2020.101263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322071/
https://www.ncbi.nlm.nih.gov/pubmed/32585596
http://dx.doi.org/10.1016/j.isci.2020.101263

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