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Titanium Tackles the Endoplasmic Reticulum: A First Genomic Study on a Titanium Anticancer Metallodrug

PhenolaTi is an advanced non-toxic anticancer chemotherapy; this inert bis(phenolato)bis(alkoxo) Ti(IV) complex demonstrates the intriguing combination of high and wide efficacy with no detected toxicity in animals. Here we unravel the cellular pathways involved in its mechanism of action by a first...

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Detalles Bibliográficos
Autores principales: Miller, Maya, Mellul, Anna, Braun, Maya, Sherill-Rofe, Dana, Cohen, Emiliano, Shpilt, Zohar, Unterman, Irene, Braitbard, Ori, Hochman, Jacob, Tshuva, Edit Y., Tabach, Yuval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322074/
https://www.ncbi.nlm.nih.gov/pubmed/32585595
http://dx.doi.org/10.1016/j.isci.2020.101262