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NRF2 pathway activation by KEAP1 inhibition attenuates the manifestation of aging phenotypes in salivary glands

Saliva plays an essential role in the maintenance of oral health. The oral cavity environment changes during aging mainly due to alterations in the secretion and composition of saliva. In particular, unstimulated basal salivary flow decreases with age. The functional decline of the salivary glands i...

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Detalles Bibliográficos
Autores principales: Wati, Sisca Meida, Matsumaru, Daisuke, Motohashi, Hozumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322188/
https://www.ncbi.nlm.nih.gov/pubmed/32590331
http://dx.doi.org/10.1016/j.redox.2020.101603