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NRF2 pathway activation by KEAP1 inhibition attenuates the manifestation of aging phenotypes in salivary glands
Saliva plays an essential role in the maintenance of oral health. The oral cavity environment changes during aging mainly due to alterations in the secretion and composition of saliva. In particular, unstimulated basal salivary flow decreases with age. The functional decline of the salivary glands i...
Autores principales: | Wati, Sisca Meida, Matsumaru, Daisuke, Motohashi, Hozumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322188/ https://www.ncbi.nlm.nih.gov/pubmed/32590331 http://dx.doi.org/10.1016/j.redox.2020.101603 |
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