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Antidepressant Effects of (S)-Ketamine through a Reduction of Hyperpolarization-Activated Current I(h)
Compelling evidence suggests that a single sub-anesthetic dose of (R,S)-ketamine exerts rapid and robust antidepressant effects. However, the cellular mechanisms underlying the antidepressant effects of (R,S)-ketamine remain unclear. Here, we show that (S)-ketamine reduced dendritic but not somatic...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322259/ https://www.ncbi.nlm.nih.gov/pubmed/32629607 http://dx.doi.org/10.1016/j.isci.2020.101239 |