Key considerations for comprehensive validation of an RNA fusion NGS panel

OBJECTIVES: Validation of RNA-based NGS assays for the detection of therapeutically targetable gene fusions is challenging. Here, we report systematic validation and quality control monitoring of our targeted fusion panel for the detection of 17 clinically relevant fusion transcripts across several...

Descripción completa

Detalles Bibliográficos
Autores principales: Barua, Subit, Wang, Gary, Mansukhani, Mahesh, Hsiao, Susan, Fernandes, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322345/
https://www.ncbi.nlm.nih.gov/pubmed/32613069
http://dx.doi.org/10.1016/j.plabm.2020.e00173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322345/
https://www.ncbi.nlm.nih.gov/pubmed/32613069
http://dx.doi.org/10.1016/j.plabm.2020.e00173

Ejemplares similares