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Long Term Culture of Human Kidney Proximal Tubule Epithelial Cells Maintains Lineage Functions and Serves as an Ex vivo Model for Coronavirus Associated Kidney Injury

The mechanism of how SARS-CoV-2 causes severe multi-organ failure is largely unknown. Acute kidney injury (AKI) is one of the frequent organ damage in severe COVID-19 patients. Previous studies have shown that human renal tubule cells could be the potential host cells targeted by SARS-CoV-2. Traditi...

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Detalles Bibliográficos
Autores principales: Xia, Siyu, Wu, Ming, Chen, Si, Zhang, Tao, Ye, Lina, Liu, Jun, Li, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322379/
https://www.ncbi.nlm.nih.gov/pubmed/32602046
http://dx.doi.org/10.1007/s12250-020-00253-y