Boning up: amino-bisphophonates as immunostimulants and endosomal disruptors of dendritic cell in SARS-CoV-2 infection

Amino-bisphosphonates such as zoledronic acid (ZA) can possibly ameliorate or prevent severe COVID-19 disease by at least three distinct mechanisms: (1) as immunostimulants which could boost γδ T cell expansion, important in the acute response in the lung; (2) as DC modulators, limiting their abilit...

Descripción completa

Detalles Bibliográficos
Autores principales: Brufsky, Adam, Marti, Juan Luis Gomez, Nasrazadani, Azadeh, Lotze, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322393/
https://www.ncbi.nlm.nih.gov/pubmed/32600410
http://dx.doi.org/10.1186/s12967-020-02433-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322393/
https://www.ncbi.nlm.nih.gov/pubmed/32600410
http://dx.doi.org/10.1186/s12967-020-02433-6

Ejemplares similares