Cargando…

Germline and sporadic cancers driven by the RAS pathway: parallels and contrasts

Somatic mutations in RAS and related pathway genes such as NF1 have been strongly implicated in the development of cancer while also being implicated in a diverse group of developmental disorders named the ‘RASopathies’, including neurofibromatosis type 1 (NF1), Noonan syndrome (NS), Noonan syndrome...

Descripción completa

Detalles Bibliográficos
Autores principales: Dunnett-Kane, V., Burkitt-Wright, E., Blackhall, F.H., Malliri, A., Evans, D.G., Lindsay, C.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322396/
https://www.ncbi.nlm.nih.gov/pubmed/32240795
http://dx.doi.org/10.1016/j.annonc.2020.03.291