Delving deep into the structural aspects of a furin cleavage site inserted into the spike protein of SARS-CoV-2: A structural biophysical perspective

One notable feature of the SARS-CoV-2 genome, the spike (S) protein of SARS-CoV-2 has a polybasic furin cleavage site (FCS) at its S1-S2 boundary through the insertion of 12 nucleotides encoding four amino acid residues PRRA. Quite intriguingly, this polybasic FCS is absent in coronaviruses of the s...

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Detalles Bibliográficos
Autor principal: Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322478/
https://www.ncbi.nlm.nih.gov/pubmed/32622243
http://dx.doi.org/10.1016/j.bpc.2020.106420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322478/
https://www.ncbi.nlm.nih.gov/pubmed/32622243
http://dx.doi.org/10.1016/j.bpc.2020.106420

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