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Computational prediction of protein aggregation: Advances in proteomics, conformation-specific algorithms and biotechnological applications

Protein aggregation is a widespread phenomenon that stems from the establishment of non-native intermolecular contacts resulting in protein precipitation. Despite its deleterious impact on fitness, protein aggregation is a generic property of polypeptide chains, indissociable from protein structure...

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Detalles Bibliográficos
Autores principales: Santos, Jaime, Pujols, Jordi, Pallarès, Irantzu, Iglesias, Valentín, Ventura, Salvador
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322485/
https://www.ncbi.nlm.nih.gov/pubmed/32637039
http://dx.doi.org/10.1016/j.csbj.2020.05.026