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Opportunities for multiscale computational modelling of serotonergic drug effects in Alzheimer's disease
Alzheimer's disease (AD) is an age-specific neurodegenerative disease that compromises cognitive functioning and impacts the quality of life of an individual. Pathologically, AD is characterised by abnormal accumulation of beta-amyloid (Aβ) and hyperphosphorylated tau protein. Despite research...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pergamon Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322519/ https://www.ncbi.nlm.nih.gov/pubmed/32380022 http://dx.doi.org/10.1016/j.neuropharm.2020.108118 |