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Nucleic Acid Sensors and Programmed Cell Death

Nucleic acids derived from microorganisms are powerful triggers for innate immune responses. Proteins called RNA and DNA sensors detect foreign nucleic acids and, in mammalian cells, include RIG-I, cGAS, and AIM2. On binding to nucleic acids, these proteins initiate signaling cascades that activate...

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Detalles Bibliográficos
Autores principales: Maelfait, Jonathan, Liverpool, Layal, Rehwinkel, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322524/
https://www.ncbi.nlm.nih.gov/pubmed/31786265
http://dx.doi.org/10.1016/j.jmb.2019.11.016