Safety and immunogenicity of a parenteral trivalent P2-VP8 subunit rotavirus vaccine: a multisite, randomised, double-blind, placebo-controlled trial

BACKGROUND: A monovalent, parenteral, subunit rotavirus vaccine was well tolerated and immunogenic in adults in the USA and in toddlers and infants in South Africa, but elicited poor responses against heterotypic rotavirus strains. We aimed to evaluate safety and immunogenicity of a trivalent vaccin...

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Detalles Bibliográficos
Autores principales: Groome, Michelle J, Fairlie, Lee, Morrison, Julie, Fix, Alan, Koen, Anthonet, Masenya, Maysseb, Jose, Lisa, Madhi, Shabir A, Page, Nicola, McNeal, Monica, Dally, Len, Cho, Iksung, Power, Maureen, Flores, Jorge, Cryz, Stanley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science ;, The Lancet Pub. Group 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322558/
https://www.ncbi.nlm.nih.gov/pubmed/32251641
http://dx.doi.org/10.1016/S1473-3099(20)30001-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322558/
https://www.ncbi.nlm.nih.gov/pubmed/32251641
http://dx.doi.org/10.1016/S1473-3099(20)30001-3

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