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Transcriptome changes during the initiation and progression of Duchenne muscular dystrophy in Caenorhabditis elegans

Duchenne muscular dystrophy (DMD) is a lethal, X-linked disease characterized by progressive muscle degeneration. The condition is driven by nonsense and missense mutations in the dystrophin gene, leading to instability of the sarcolemma and skeletal muscle necrosis and atrophy. Resulting changes in...

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Detalles Bibliográficos
Autores principales: Hrach, Heather C, O’Brien, Shannon, Steber, Hannah S, Newbern, Jason, Rawls, Alan, Mangone, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322572/
https://www.ncbi.nlm.nih.gov/pubmed/32227114
http://dx.doi.org/10.1093/hmg/ddaa055