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Transcriptome changes during the initiation and progression of Duchenne muscular dystrophy in Caenorhabditis elegans
Duchenne muscular dystrophy (DMD) is a lethal, X-linked disease characterized by progressive muscle degeneration. The condition is driven by nonsense and missense mutations in the dystrophin gene, leading to instability of the sarcolemma and skeletal muscle necrosis and atrophy. Resulting changes in...
Autores principales: | Hrach, Heather C, O’Brien, Shannon, Steber, Hannah S, Newbern, Jason, Rawls, Alan, Mangone, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322572/ https://www.ncbi.nlm.nih.gov/pubmed/32227114 http://dx.doi.org/10.1093/hmg/ddaa055 |
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