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Apatinib Inhibits the Invasion and Metastasis of Liver Cancer Cells by Downregulating MMP-Related Proteins via Regulation of the NF-κB Signaling Pathway

OBJECTIVE: We aimed to investigate whether apatinib has an inhibitory effect on the invasion and metastasis of liver cancer in vitro. METHODS: The anti-invasion and antimetastasis effects of apatinib in HepG2, Hep3B,Huh7 and SMMC-7721 liver cancer cell lines were tested by the wound-healing and tran...

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Detalles Bibliográficos
Autores principales: He, Xiaoxiao, Huang, Zaozao, Liu, Ping, Li, Qiuting, Wang, Mengmeng, Qiu, Mengjun, Xiong, Zhifan, Yang, Shengli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322602/
https://www.ncbi.nlm.nih.gov/pubmed/32685465
http://dx.doi.org/10.1155/2020/3126182